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PhD positions: In Institute of Biochemistry, Jena University Hospital - Friedrich Schiller University Jena, Germany



PhD positions: In Institute of Biochemistry, Jena University Hospital - Friedrich Schiller University Jena, Germany 🇩🇪.
Subjects:
Neurobiology / Imaging
Description:
1 PhD position in Neurobiology / Imaging
Prof. Britta Qualmann, Inst. of Biochem. I, UKJ - Friedrich Schiller University Jena, Germany
Prof. Christian Geis, Section of Translat. Neuroimmunol., Dept. Neurol., UKJ
We seek for a productive addition to our research team in a collaborative project. We plan to study pathomechanisms of synaptic changes underlying autoimmune disorders of the central nervous system applying super-resolution microscopy.
The Geis lab examines immune-mediated changes of synapses by interactions with pathogenic human antibodies against neuronal proteins. Short- and long-term effects on neuronal networks are analyzed using electrophysiological and various microscopy methods.
The Qualmann lab is an internationally well-known lab that focusses on proteins with the power to shape the dendritic arbor of neurons, which is important for network formation and synaptic plasticity, as well as on molecular mechanisms used by such proteins (direct membrane shaping; force generation by local actin nucleation).
The project combines the expertise of both labs and thus offers excellent opportunitie to work on a hot field of cell/neurobiology with broad and state-of-the-art methods and equipment.
For related former PhD projects in our labs e.g. see Koch et al. 2011 EMBO J; Schneider et al. 2014 J Cell Biol; Hou et al., 2015 PLoS Biology; Grünewald et al. 2017 Elife; Haselmann et al. 2018 Neuron; Petit-Pedrol, Sell et al. 2018 Brain; Wolf et al. 2019 Nat Cell Biol.
Applicants should have solid theoretical and practical knowledge of and interests in cell/neurobiology and in fluorescence microscopy as well as in quantitative image analyses.

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